Product category:
Measurement and Quality Software and SPC
News Release from: Cerno Bioscience
Edited by the Manufacturingtalk Editorial
Team on 26 October 2006
Agreement on data analysis software
Cerno Bioscience has announced two major agreements have been reached with leading research institutes in China for the use of its ground-breaking MS data analysis software, MassWorks.
Cerno Bioscience has announced two major agreements have been reached with leading research institutes in China for the use of its ground-breaking MS data analysis software, MassWorks Cerno has entered into collaborative research in drug metabolism with Dr Dafang Zhong, Director of Drug Metabolism Research at Shanghai Institute of Materia Media, Chinese Academy of Sciences
This article was originally published on Manufacturingtalk on 14 Mar 2006 at 8.00am (UK)
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Cerno Bioscience has announced MassWorks, an easy-to-use post acquisition software package that utilizes Cerno's patented MSIntegrity technology to achieve high mass accuracy.
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Cerno Bioscience has announced the environmental application of its trailblazing MassWorks software.
Cerno has also signed an agreement with Egret Pharma (Shanghai) Limited for extensive use of the MassWorks software in small molecule synthesis.
Research by Dr Zhong will focus on obtaining high mass accuracy to aid in metabolite identification using conventional mass spectrometry systems by applying MassWorks.
The triple quadrupole systems are specified to provide only rudimentary mass accuracy and therefore lack the high mass accuracy capabilities of a high resolution system considered necessary for metabolite identification.
Further reading
Determination of elemental composition
A new publication from Cerno Bioscience reveals that its award winning MassWorks will determine elemental composition with an ion trap at unit mass resolution without the need for skilled operators.
Automated and parameter-free peak integration
A new paper from Cerno Bioscience and XenoBiotic Laboratories, is now available called 'Automated and Parameter-Free Peak Integration for LC/MS/MS Quantitation'.
Metabolism researchers will be able to achieve the results of a high-end spectrometer for a fraction of the investment when applying MassWorks' MSIntegrity calibration technology, which improves mass accuracy by up to 100x.
In addition to enhancing and confirming the identity of various metabolites, the software will also improve the signal-to-noise and peak shape of the MS data to further enable elemental composition determination on these unit mass resolution MS systems.
The agreement with Egret Pharma, a leading Chinese pharmaceutical research and development company, will see the company using Cerno's MassWorks software extensively in its small molecule synthesis studies to significantly shorten the turn-around time in the drug discovery process.
MassWorks will be used to confirm the identity of target compounds as well as to identify synthesis by-products, impurities and degradation products, all using conventional unit mass resolution MS systems.
This identification will provide timely feedback to the organic chemists to reduce turn-around time.
MassWorks utilises Cerno's DirectRead technology to read most instrument data formats directly, eliminating the need for importing or exporting MS data to the clipboard or utilizing intermediate exchange formats.
This saves time, reduces transcription errors, simplifies file management, and saves substantial disk space.
As DirectRead does not alter the original data, it assists compliance with common regulatory requirements such as GLP and the FDA's 21 CFR Part 11.
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