Product category:
Measurement and Quality Software and SPC
News Release from: Cerno Bioscience | Subject: Compound identification
Edited by the Manufacturingtalk Editorial
Team on 17 April 2007
Accurate compound identification for
analysts
Cerno Bioscience has announced a new application note for its MassWorks software which enables elemental analysts to carry out accurate compound identification on LC/MS single quadrupole instruments.
Cerno Bioscience has announced the availability of a new application note for its MassWorks software The application note describes how MassWorks enables elemental analysts to carry out accurate compound identification on LC/MS single quadrupole instruments, even at unit mass resolution
This article was originally published on Manufacturingtalk on 14 Mar 2006 at 8.00am (UK)
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Easy-to-use post acquisition software package
Cerno Bioscience has announced MassWorks, an easy-to-use post acquisition software package that utilizes Cerno's patented MSIntegrity technology to achieve high mass accuracy.
Accuracy from mass spectrometers with software
Cerno Bioscience has announced the environmental application of its trailblazing MassWorks software.
This unique software improves mass accuracy by up to 100X, significantly improving the ability to confirm the identity of unknown compounds.
In addition, the enhancement in signal-to-noise provided by the software can significantly lower the detection limits for compounds measured at trace levels.
The application note describes how elemental composition analysis can typically only be achieved using higher resolution systems, which can incur a much higher cost.
Further reading
Determination of elemental composition
A new publication from Cerno Bioscience reveals that its award winning MassWorks will determine elemental composition with an ion trap at unit mass resolution without the need for skilled operators.
Automated and parameter-free peak integration
A new paper from Cerno Bioscience and XenoBiotic Laboratories, is now available called 'Automated and Parameter-Free Peak Integration for LC/MS/MS Quantitation'.
MassWorks is an exciting development for elemental analysis, as it enables identification of unknown compounds even when using a low resolution instrument.
With this software, a tandem MS capability is unnecessary, as formula ID is accomplished in the full MS scan mode.
MassWorks is now available with CLIPS (Calibrated Lineshape Isotope Profile Search), which provides dramatically improved results for formula ID.
The CLIPS algorithm provides a unique level of accuracy by matching each formula candidate to the carefully calibrated mass spectrum in profile mode.
This enables highly accurate results at a lower cost, using a lower resolution system.
The easy-to-use post acquisition software package utilises Cerno's patented MSIntegrity technology to achieve high mass accuracy, offering elemental analysts substantially improved and accurate measurements utilising their existing mass spectrometer instruments.
This means that they are able to achieve the results of a high-end spectrometer for a fraction of the investment.
MassWorks is capable of the analysis of complex samples with substantial chemical backgrounds as well as that of unknown compound samples which require identification.
MassWorks also benefits from Cerno's DirectRead technology to interpret most instrument data formats directly, eliminating the need for importing or exporting MS data to the clipboard or utilising intermediate exchange formats.
This saves time, reduces transcription errors, simplifies file management, and saves substantial disk space.
As DirectRead doesn't alter the original data, it assists compliance with common regulatory requirements such as GLP.
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