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Product category: Programming aids and applications
News Release from: Chip-Man Technologies | Subject: Cell-IQ
Edited by the Manufacturingtalk Editorial Team on 16 June 2006

Chip-Man Collaborates with TCS CellWorks

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Cell-IQ live cell imaging technology to be used to enhance angiogenesis research.

Chip-Man Technologies Limited and TCS CellWorks have announced a technology collaboration, whereby Chip-Man Technologies' novel Cell-IQ continuous cell culturing platform will be used with TCS CellWorks' AngioKit model This will provide unprecedented levels of content and throughput in angiogenesis research

Terry Cartwright, CEO, TCS CellWorks commented, "TCS CellWorks produces information-rich in vitro models based on cultured human cells for drug discovery and functional analysis." He continued, "We are delighted with the results obtained in collaboration with Chip-Man Technologies and their new Cell-IQ cell analysis system".

"This raises our ability to track cell proliferation, migration and differentiation within a complex co-culture model to a new level".

Cell-IQ enables even the most subtle changes in cellular growth and tubule formation to be recorded and monitored kinetically.

This is a distinct advantage to observe the hidden events of key biological processes such as angiogenesis.

Juha Korpinen, CEO, Chip-Man Technologies added, "We welcome the opportunity to work with TCS CellWorks".

"They have a range of products to which Cell-IQ will bring additional value." Cell-IQ is a continuous cell culturing platform, optimized for the real-time analysis of morphological and physiological events in living cells, co-cultures, primary cells and monolayer tissue models.

The fully integrated, ultra-precise 'machine vision' technology, controls all detection and environmental systems.

As a result the Cell-IQ learns to identify, follow and measure morphological change in individual cells without traditional labels or dyes.

TCS CellWorks' AngioKit offers a cell-based system using solely human cell-lines, for quantitatively assessing both pro- and anti-angiogenic agents.

The kit is provided in 24-well plate format and is suitable for low volume screening applications.

Angiogenesis is the multi-step process by which new blood vessels develop from existing vasculature.

It is the subject of intense research activity at present since the controlled modulation of angiogenesis offers the possibility of novel therapeutic approaches to several important diseases including cardiovascular disease, arthritic disease, cancer, psoriasis and diabetic retinopathy.

TCS CellWorks has developed the first, true, in vitro human model of angiogenesis which is rapidly becoming accepted as the best and most predictive model available.

With Chip-Man Technologies' Cell-IQ, the full potential of the AngioKit can now be realised and angiogenesis research significantly enhanced.

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