Product category:
Materials Testing
News Release from: Malvern Instruments | Subject: Nano particle and molecular characterisation
Edited by the Manufacturingtalk Editorial
Team on 01 March 2007
Nano particle and molecular
characterisation
The 'chromatography flow-mode' option for Malvern's Zetasizer Nano particle and molecular characterisation system, enables its use as an in-line chromatography detector.
Launched at Pittcon 2007 the 'chromatography flow-mode' option for Malvern's Zetasizer Nano particle and molecular characterisation system, enables its use as an in-line chromatography detector A significant new development, 'chromatography flow-mode' permits the coupling of dynamic light scattering with size exclusion chromatography, conferring the ability to perform Absolute Size Exclusion Chromatography (ASEC)
This article was originally published on Manufacturingtalk on 9 Jan 2008 at 8.00am (UK)
Related stories
Control particle size, measurement and moisture
Two companies will be showing the latest developments in particle sizing systems for solids processing and infrared sensors for on-line measurement and control of moisture and composition.
Particle measurement aids paint performance
Instrument performs zeta potential and particle size measurement in developing the use of nanosized ceramic particles to enhance scratch resistance for automotive lacquers.
This allows protein size to be measured directly rather than relying on column calibration or additional data from a second detector, and means that molecular weight standards are no longer required to identify oligomeric species or determine protein purity.
To use the Zetasizer Nano as an absolute light scattering detector it simply needs to be connected after the last detector in a size exclusion chromatography (SEC) system.
The instrument can be added to any SEC set-up; no column calibration is required and the Zetasizer Nano's software makes the entire measurement process simple and straightforward.
For the majority of protein separations in aqueous media, no extra parameters are required.
Size is plotted in real time as material is eluted from the column, and the molecular weight of each peak is calculated automatically at the end of the measurement.
The Zetasizer Nano was designed specifically to meet the low concentration and small sample volume requirements of protein and other biomolecular applications and is now in widespread use.
It is by applying the system's patented optical design and high sensitivity capabilities to real time flow measurements that Malvern has facilitated the Zetasizer Nano's use as a chromatography detector, providing a major new tool for protein researchers. Request a free brochure from Malvern Instruments ...
• Malvern Instruments: contact details and other news
• Email this article to a colleague
• Register for the free Manufacturingtalk email newsletter
• Manufacturingtalk Home Page
Search the Pro-Talk network of sites
