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Analytical Companion For The QA Lab

A Metrohm UK product story
Edited by the Manufacturingtalk editorial team Aug 23, 2004

Pharm PAC contains the titration methods most used in the pharmaceutical industry in an attractive and practical form.

Pharm PAC stands for Pharmaceutical Potentiometric Analysis Collection.

It contains the titration methods most used in the pharmaceutical industry in an attractive and practical form.

Pharm PAC Methods Know-how package for the determination of pharmaceutical ingredients.

The 35 methods delivered with this package can easily be loaded into a Metrohm Titrino or Titrando titrators Overview of the Pharm PAC Methods A.

Aqueous acid-base titrations A 1 Direct titrations Titrations with bases Titrations with acids A 2 Indirect titrations (back titrations) B.

Nonaqueous acid-base titrations B 1 Alkaline titrants In ethanol, with HCl addition In dimethylformamide (DMF) In acetone In pyridine In ethanol or methanol In special solvents B 2 Acidic titrants In glacial acetic acid, with HClO4 In glacial acetic acid/acetic anhydride, with HClO4 In acetic anhydride, with HClO4 In glacial acetic acid plus Hg acetate, with HClO4 In glacial acetic acid/MEK, with HClO4 In formc acid/glacial acetic acid or acetic anhydride, with HClO4 In other solvents or solvent mixtures C.

Redox titrations C 1 Iodine/thiosulfate (iodometry) C 2 Iodine/arsenite (iodometry) C 3 Diazotization with NaNO2 C 4 Cer(IV) (cerimetry) C 5 KBrO3 (bromatometry) C 6 KMnO4 (permanganometry) C 7 KIO3 C 8 Reducing sugars D.

Precipitation titrations D 1 AgNO3 (argentometry) D 2 Surfactant titrations E.

Photometric EDTA titrations (chelometry/complexometry) F.

Characteristic numbers of fats and oils F 1 Acid Value and Free Fatty Acids (FFA) F 2 Hydroxyl Value F 3 Iodine Value F 4 Peroxide Value F 5 Saponification Value G.

Qualification of the titrator, validation of a titration method The methods included in the Metrohm Pharm PAC take into account the latest standards.

They apply the most appropriate methods and they use the Metrosensors especially developed for non-aqueous titrations.

By using these methods directly as SOPs (Standard Operating Procedures) in your laboratory, you will save both time and money.

Pharm PAC comprises a ring binder with detailed method descriptions, method memory card, CD ROM with Pharm PAC methods and Metrodata software CD.

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