Product category:
Materials Testing
News Release from: Selerity Technologies | Subject: Technical note (HTLC)
Edited by the Manufacturingtalk Editorial
Team on 07 August 2003
Preheating Requirements In Liquid
Chromatography
A new technical note aimed at laboratory managers is intended to introduce readers to the performance benefits accrued from pre-heating of the mobile phase in high temperature liquid chromatography.
Extended temperature separations specialist Selerity Technologies, has produced a new free technical note detailing preheating requirements in High Temperature Liquid Chromatography (HTLC) The new technical note is aimed at laboratory managers, especially in the pharmaceutical industry
This article was originally published on Manufacturingtalk on 25 Sep 2003 at 8.00am (UK)
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Application Note Shows Better Separation Results
Selerity Technologies has produced a new free application note showing how laboratory managers can enhance the benefits of elevated temperatures in High Performance Liquid Chromatography.
Selerity's new technical note is intended to introduce readers to the performance benefits accrued from pre-heating of the mobile phase in high temperature liquid chromatography.
The note describes how preheating of the mobile phase is significant in attaining maximum performance in HTLC, since the relationship between temperature and viscosity strongly influences the mobile phase flow profile and the diffusion characteristics.
A new highly responsive low-volume, low-mass solvent preheater has been designed by Selerity to keep the amount of tubing required for preheating the mobile phase low, and without invading the fluid path.
With preheating, peaks are sharper and resolution is greatly improved.
This highly responsive preheater design makes temperature programming possible with the most commonly used chromatographic columns, without loss of efficiency.
The note describes the flow rates necessary to bring the mobile phase to the temperature of the separation column.
This new low mass preheater is able to respond quickly for temperature programming applications, and temperature program rates in excess of 25 and 730C/min are possible at full power over a range of flows and mobile phase compositions.
The new mobile phase preheater described in Selerity's technical note is ideal for use in controllably heated to over 200C mobile phases and over a wide range of flows.
Fast heating and rapid cool-down at the conclusion of temperature programmed runs are possible, which is essential for fast analytical methods at high sample throughput rates.
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